Although the precise composition of propolis depends on the zone of beehive activity (climate, surrounding vegetation, and so on), as a rough guide, we can mention the following: resins and balsams (50-60%), waxes (20-25%), essential oils (5-10%), pollen (5%), others (minerals, enzymes, etc. 5%).

The fraction of resins and balsams is the one that contains most of the biologically active compounds, mainly phenolic ones derived from the vegetable kingdom and having proven pharmacological abilities. Due to the great number of active ingredients present, tincture (alcoholic extract) of propolis is well-known and used for its therapeutic properties, principally for its stimulant action on the organism's defence system. Notable amongst its properties are its antioxidant and anti-microbial action, its activity as a stimulant and its healing, analgesic, anaesthetic and anti-inflammatory activity.

The study of the biological activity of this product was undertaken following two lines of work: (a) a study of the antioxidant activity and (b) a study of the anti-microbial action.

Source: Elhuyar Fundazioa

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