In the study, overweight men and women with measured characteristics of MetS were given a diet and aerobic exercise plan that included supervised exercise five days a week, for 4-6 months. After losing weight, participants underwent programmed weight regain and were separated into two groups, one that exercised and one that didn't. The non-exercise group experienced rapid deterioration in weight-loss induced benefits to metabolic health. The exercise group maintained improvements in almost all measures, including LDL and HDL cholesterol, oxygen consumption (VO2max), blood pressure and glucose. Exercise didn't maintain blood cholesterol and abdominal fat loss.

"It's clear that the message to lose weight isn't working because so many people regain weight; a new message is to keep exercising and maintain your weight to reduce disease risk and improve overall health," Thomas said. "Don't worry so much about losing weight, but focus on exercising and maintaining your current weight."

Source: University of Missouri-Columbia