"The protective effect of tall stature is likely to be a proxy for environmental factors from birth up to puberty which affect both growth of the bones in the legs and also have a long term effect on heart disease in the future." Dr Debbie Lawlor
Unsurprisingly, women with heart disease were more likely to be older, more obese and to be former or current smokers than women who did not have heart disease. They were also more likely to have poorer lung function, to have higher cholesterol levels, to be more insulin resistant “ a precursor to diabetes “ and to come from working class families. But they were also more likely to have shorter trunks and legs.
When all the potential risk factors were taken into account, leg length remained strongly linked to risk of heart disease with this risk decreasing by an average of 16 per cent for every increase of 4.3 cm in leg length.
Dr Lawlor said: The protective effect of tall stature is unlikely to be the result of wider arteries or to less height shrinkage with age. Rather it is likely to be a proxy for environmental factors from birth up to puberty which affect both growth of the bones in the legs and also have a long term effect on heart disease in the future.
Breast feeding, high energy diets at the age of two and being born into an affluent family all positively influence growth; having parents who smoke and being born into a poor family negatively influence growth. The association between leg length and heart disease suggests that these early life risk factors also cause heart disease.
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