The investigators found that dry-weight can be assessed inexpensively through relative plasma volume monitoring (which uses photo-optical technology to assess changes in volume of a patient's blood) and body impedance analysis (which determines lean body mass). They also discovered that restricting salt intake can help control blood pressure and make it easier for patients to get down to a proper dry-weight. Studies suggest that salt restriction and dry-weight reduction through dialysis together provide more benefits to the heart than antihypertensive medications. This could have important clinical implications because most patients with chronic kidney disease die from cardiovascular causes.

The authors concluded that "medication-directed approaches for blood pressure control should be a secondary consideration to manipulating the diet and dialysis prescription in order to achieve dry-weight."

Reducing salt intake is getting easier now that many restaurants and packaged food companies are participating in the National Salt Reduction Initiative, a public-private partnership formed to combat America's over-consumption of salt. Their goal is to reduce sodium in their products by 20% over the next five years. Also, the U.S. Food and Drug Administration is planning to launch an initiative later this year to reduce Americans' salt intake by imposing legal limits on the amount of sodium allowed in processed food.

SOURCE Clinical Journal of the American Society Nephrology