Study co-authors include Magali Giral, MD, PhD, Yohann Foucher, PhD, Georges Karam, MD, Yann Labrune, Pascal Daguin (ITERT); Mich le Kessler, MD (Centre Hospitalier Universitaire de Brabois); Bruno Hurault de Ligny, MD (Centre Hospitalier Universitaire de Clemenceau); Mathias B chler, MD, PhD (Centre Hospitalier Universitaire de Bretonneau); Fran?§ois Bayle, MD (Centre Hospitalier Universitaire de Grenoble); Carole Meyer, MD (Centre Hospitalier Universitaire de Strasbourg); Nathalie Trehet, Karine Renaudin, MD, and Anne Moreau, MD (Centre Hospitalier Universitaire de Nantes).

In reviewing the results of Professor Soulillou's study in an accompanying editorial, Ron Shapiro, MD (University of Pittsburgh) stated that "the authors are to be congratulated for describing a novel measure that may have important implications for long-term outcomes in renal allograft recipients." He noted, however, that because living donors made up less than 1% of the study's cases, it is not clear if the findings hold true for recipients other than those who receive deceased donor kidneys.

Also, Dr. Shapiro noted that kidneys from very young pediatric donors might be associated with different outcomes, particularly if two kidneys from one child are transplanted into an adult, as is commonly done). According to a 2009 study in the Clinical Journal of the American Society of Nephrology (CJASN), a single kidney from a very young deceased donor maintains the health of an adult with kidney failure.1 Other studies have reported more complications when single kidneys from very young donors are transplanted into adults.

SOURCE American Society of Nephrology